Table 3 Number and percentage of eyes with subclinical CI-DMO and CI-DMO by ETDRS group at baseline (V1) and at the 3-year follow-up visit (V4) and respective LOR fluctuations and BCVA variations.

From: Characterisation of progression of macular oedema in the initial stages of diabetic retinopathy: a 3-year longitudinal study

 

Subclinical CI-DMO (CRT ≥ 1 SD and <2SD)

CI-DMO (CRT ≥ 2 SD)

 

ETDRS 10–20

ETDRS 35

ETDRS 43–47

ETDRS 10-20

ETDRS 35

ETDRS 43–47

Baseline (V1)

9/23 (39%)

10/31 (32%)

6/20 (30%)

2/23 (9%)

3/31 (10%)

3/20 (15.0%)

3-year Visit (V4)

6/23 (26%)

10/31 (32%)

8/20 (40%)

2/23 (9%)

2/31 (7%)

2/20 (10.0%)

Number of eyes with increased LOR ratio (≥1SD)

 

Subclinical CI-DMO

CI-DMO

 

ETDRS 10–20

ETDRS 35

ETDRS 43–47

ETDRS 10–20

ETDRS 35

ETDRS 43–47

Baseline (V1)

2/9 (22%)

4/10 (40%)

3/6 (50%)

1/2 (50%)

1/3 (33%)

1/3 (33%)

3-year Visit (V4)

3/6 (50%)

7/10 (70%)

7/8 (88%)

2/2 (100%)

2/2 (100%)

2/2 (100%)

LOR fluctuations and BCVA variations over the follow-up period of subclinical CI-DMO or CI-DMO eyes

 

Vision Gain

No Vision Change

Vision Loss

Without LOR fluctuations

8 (67%)

2 (29%)

2 (18%)

With LOR fluctuations

4 (33%)

5 (71%)

9 (82%)

 

12

7

11

  1. CI-DMO centre-involving diabetic macular oedema, CRT central retinal thickness, SD standard deviation, LOR low optical reflectivity, BCVA best-corrected visual acuity.