Table 3 Comparison of Vitamin D level among studied VDR genotypes in KC patients.
From: Thyroid gland dysfunction and vitamin D receptor gene polymorphism in keratoconus
Parameter | Taq I genotypes | P value | |||
|---|---|---|---|---|---|
TT (n = 37patients) | Tt (n = 80 patients) | tt (n = 60 patients) | |||
Vitamin D level (ng/ml) | Median (Min–Max) | 19.3 (10.0–62.0) | 10.2 (7.6–51.0) | 9.5 (6.9–42.0) | <0.001 |
Vitamin D groups | Sufficiency n (%) | 10 (27.0%) | 5 (6.2%) | 4 (6.7%) | <0.001 |
Insufficiency n (%) | 27 (73.0%) | 48 (60.0%) | 20 (33.3%) | ||
Deficiency n (%) | 0 (0.0%) | 27 (33.8%) | 36 (60.0%) | ||
Parameter | Apa I genotypes | P value | |||
|---|---|---|---|---|---|
AA (n = 64) | Aa (n = 85) | aa (n = 28) | |||
Vitamin D level (ng/ml) | Median (Min–Max) | 12.8 (7.6–62.0) | 10.4 (7.5–59.0) | 9.9 (6.9–51.0) | 0.243 |
Vitamin D groups | Sufficiency n (%) | 11 (17.2%) | 7 (8.2%) | 1 (3.6%) | 0.072 |
Insufficiency n (%) | 35 (54.7%) | 48 (56.5%) | 12 (42.8%) | ||
Deficiency n (%) | 18 (28.1%) | 30 (35.3%) | 15 (53.6%) | ||
Parameter | Bsm I genotypes | P value | |||
|---|---|---|---|---|---|
BB (n = 61) | Bb (n = 75) | bb (n = 41) | |||
Vitamin D level (ng/ml) | Median (Min–Max) | 12.0 (6.9–62.0) | 10.0 (7.3–59.0) | 12.8 (7.6–42.0) | 0.567 |
Vitamin D groups | Sufficiency n (%) | 4 (6.6%) | 8 (10.7%) | 7 (17.1%) | 0.441 |
Insufficiency n (%) | 37 (60.7%) | 38 (50.7%) | 20 (48.8%) | ||
Deficiency n (%) | 20 (32.7%) | 29 (38.6%) | 14 (34.1%) | ||
