Table 4 Risk of bias using adapted Newcastle–Ottawa Quality Assessment Scale: Cohort Studies.
From: Predictors of emotional distress in uveal melanoma survivors: a systematic review
Selection | Outcome | ||||
|---|---|---|---|---|---|
Study | Representative of the exposed cohort? | Ascertainment of exposure? | Assessment of outcome? | Was follow-up long enough for outcomes to occur? | Adequacy of follow up cohorts? |
Brandberg et al. [42] | Yes - Different tumour sizes, treatments, equal men and women, age range | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 2 months | Yes - subjects lost to follow up unlikely to introduce bias – small number lost (86%) and description provided of those lost. |
Brown et al. [32] | Different tumour types and treatment, male and female. Age not reported. | Yes - Clinical records and self-report | Yes - Validated measures of emotional distress | Yes –12 months | Yes - subjects lost to follow up unlikely to introduce bias – moderate number lost (63.5%) and description provided of those lost. |
Brown et al. [35] | Choroid and ciliary body, equal men and women, age limited to 69 (+−12), No description of tumour type or size. | Yes - Clinical records and self-report | Yes - Validated measures of emotional distress | Yes – 12 months | Partially - no percentage reported, some lost at follow up, some description of those lost |
Brown et al. [36] | Unclear - Ciliary body and choroidal melanoma, treatment type varied. No description of age, gender or tumour size. | Yes - Clinical records and self-report | Yes - Validated measures of emotional distress | Yes – 12 months | No - large number lost at follow up (55.7%), no description of those lost |
Damato et al. [38] | Yes -, Different size and tumour characteristics (choroidal only), varying treatment, male and female and age. | Yes - Clinical records and self-report | Yes - Validated measures of emotional distress | Yes – 12 months | No description or percentage. |
Damato et al. [37] | Yes - Different size and tumour characteristics (choroidal only), varying treatment, male and female and age | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 12 months | No description or percentage. |
Hope-Stone et al. [33] | Yes - Different tumour characteristics, treatment, male and female, age range 54–70 (average age for UM 65) | Yes - Clinical records and self-report | Partially- Subscale for worry from a complete validated measure used | Yes – 12 months | Partially - high number of subjects lost to follow up, (59.3 %), no description |
Hope-Stone et al. [34] | Yes - Age, gender, tumour type, treatment | Yes, Clinical records and self-report | Yes - Validated measures of emotional distress | Yes – 12 months | Yes - Subjects lost to follow up unlikely to introduce bias – moderate number lost (74.2%) and description provided of those lost |
Klingenstein et al. [41] | Partially - Somewhat representative, one treatment modality, age range accurate, male and female, tumour types, not sizes | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 3 months | No description or percentage. |
Lieb et al. [43] | Yes - treatment modality, age range accurate, male female, tumour types and sizes | Yes - Clinical records and self-report | Yes - validated measures of emotional distress | Yes – 6 weeks | Partially - Subjects lost to follow up unlikely to introduce bias, small number lost, no percentage reported, some description of those lost |
Melia – COMS [45] | Partially - Only unilateral choroidal melanoma, accurate age, gender, tumour size and treatment | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 6 months | Yes - Subjects lost to follow up unlikely to introduce bias – small number lost (91%) and some description provided of those lost |
Schuermeyer et al. [40] | Partially - Somewhat representative, men and women, age limited to 60 (+−15), no description of tumour type size | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 3 months | Partially - Subjects lost to follow up no percentage reported but moderate proportion from sample, some description including number. |
Van Beek et al. [44] | Yes - Equal men and women, age range, treatment type, tumour size | Yes - Clinical records | Yes - Validated measures of emotional distress | Yes – 6 months | Partially - Subjects lost to follow up no percentage reported but small proportion from sample, description provided of those lost. |
