Table 1 Mean change from baseline in best corrected visual acuity (BCVA) and central subfield thickness (CST) outcomes at Month 12 (M12) and Month 24 (M24) for the treatment-naïve and non-treatment-naïve patient cohorts.

From: Evaluation of care with intravitreal aflibercept treatment for UK patients with diabetic macular oedema: DRAKO study 24-month real-world outcomes

   

Treatment-naïve

Non-treatment-naïve

   

Baseline

Change from baseline

Baseline

Change from baseline

BCVA (Letters)

M12 (N = 388)

Mean (SD)

71.4 (12.0)

2.5 (12.2)

68.8 (13.7)

0.2 (10.2)

95% CI

-

1.3, 3.8

-

−1.5, 1.8

n

375

353

166

153

M24 (N = 326)

Mean (SD)

71.5 (12.4)

0.7 (12.7)

69.5 (12.8)

−0.3 (13.0)

95% CI

-

−0.7, 2.1

-

−2.5, 1.9

n

326

326

135

135

CST (µm)

M12 (N = 169)

Mean (SD)

448.7 (88.7)

−119.1 (116.4)

419.3 (121.0)

−79.1 (137.6)

95% CI

-

−130.7, −107.4

-

−100.2, −58.0

n

388

386

169

166

M24 (N = 135)

Mean (SD)

447.6 (77.3)

−123.3 (104.3)

422.5 (117.8)

−91.6 (132.9)

95% CI

-

−134.7, −112.0

-

−114.2, −69.0

n

326

326

135

135

  1. 95% confidence intervals (CI) are stated.