Fig. 1: An illustration of the retinal vascular plexuses in red (labelled on right) hand drawn on top of a histological section of the human retina showing anatomic layers (labelled on left) from spectral domain optical coherence tomography.

The four vascular plexuses can be grouped into superficial and deep vascular complexes (SVC and DVC, as shown on right) for routine segmentation, but ought to reflect the anatomic location of the ICP at the IPL/INL interface, which the current OCTA segmentations use as a border between superficial and deep plexuses (labelled on left as SCP and DCP). Current and proposed vascular nomenclature and OCTA segmentations are shown at the bottom. (NFL nerve fibre layer, GCL ganglion cell layer, IPL inner plexiform layer, INL inner nuclear layer, OPL outer plexiform layer plus Henle’s fibre layer, ONL outer nuclear layer, PR photoreceptor layers, RPE retinal pigment epithelium, OCTA optical coherence tomography angiography, RPCP radial peripapillary capillary plexus, SVP superficial vascular plexus, ICP intermediate capillary plexus, DCP deep capillary plexus). This figure is reproduced from Campbell et al. [11], under the Creative Commons Attribution 4.0 International License. No changes to content were made. http://creativecommons.org/licenses/by/4.0/.