Table 1 Study inclusion and exclusion criteria.
Inclusion criteria |
|---|
1. No ocular pathologies other than open-angle glaucoma with a normal open angle |
2. Aged 20–70 years on completion of the consent form |
3. Glaucomatous disc/retinal changes corresponding to visual field defect according to the Anderson and Patella criteriaa |
4. Two consecutive reliable/reproducible visual field results were obtained at intervals of ≤ 3 months at the time of study entry |
5. Mean deviation (MD) within 2 dB; MD > −15 dB in both eyes at commencement of observation |
6. No application of intraocular pressure (IOP)-reducing agents for at least 6 months after such agents were discontinued before study entry |
7. IOP < 15 mmHg without treatment on at least five of six consecutive IOP measurements during the 6 months before study entry |
8. Absence of any intracranial disease that may affect the visual field |
9. No clinically significant media opacity, including cataract |
Exclusion criteria |
|---|
1. Spherical equivalent < −9.0 or > +4.0 diopters |
2. Best visual acuity < 0.8 (decimal) |
3. History of intraocular surgery or laser treatment |
4. History of uveitis, steroid use, trauma, ocular infection, or inflammatory disease |
5. History of corneal disease, retinal disease, or cataract |
6. History of diabetes mellitus or hypertension |
7. Prescription of any drug that may affect IOP or ocular blood flow |
8. Using antiplatelet and/or anticoagulant agents |
9. Eyes with disc/retinal findings suggestive of any type of congenital anomaly, including strong myopic changes and tilted disc syndrome |