Table 3 Association between IOP and annual axial elongation rate over subsequent follow-up (dependent variable) per linear mixed-effects model (2), controlling for age, sex, CCT, ACD and LT.

From: Higher intraocular pressure is associated with slower axial growth in children with non-pathological high myopia

Dependent variable: annual axial growth from time point t−1 to t (mm/y)

IV and covariates at t − 1

Mean

N

VIF

Estimate

95% CI

P

Intercept

NA 

 NA

 NA

0.20

0.16 to 0.23

<0.001

IOP (per mmHg)

16

313

1.1

−0.01

−0.02 to −0.005

0.001

Age (per year)

13

326

1.4

−0.03

−0.03 to −0.02

<0.001

IOP × Age

NA

313

1.1

0.00

0.00 to 0.00

0.08

CCT (per μm)

549

326

1.2

0.00

0.00 to 0.00

0.05

ACD (per mm)

3.2

326

1.4

0.08

−0.03 to 0.19

0.18

LT (per mm)

3.5

326

1.6

−0.10

−0.25 to 0.04

0.17

Sex: Female

NA

184

1.1

−0.03

−0.08 to 0.03

0.34

Sex: Male

NA

142

Reference

  1. IV: independent variable (IOP at time point t−1).
  2. N: number of observations where IV or covariate and axial elongation rate are available.
  3. VIF: variance inflation factor.
  4. IOP intraocular pressure, CCT central corneal thickness, ACD anterior chamber depth, LT lens thickness.