Table 2 Association between visual acuity, physical and mental health indices and the presence of ADL impairment in nAMD patients.
ADL scores | |||
|---|---|---|---|
Impaired BADLs Age/sex adjusted OR (95% CI) | Impaired IADLs Age/sex adjusted OR (95% CI) | Impaired total ADLs Age/sex adjusted OR (95% CI) | |
Visual acuity | |||
- Normal VA (>20/40) | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
- Mild VI (\(\le \)20/40 to >20/80) | 1.29 (0.77–2.18) | 1.77 (1.05–2.98) | 1.75 (1.03–3.00) |
- Moderate VI (\(\le \)20/80 to >20/200) | 3.34 (1.89–5.90) | 5.28 (2.52–11.07) | 6.22 (3.42–11.31) |
- Legally blind (\(\le \)20/200) | 1.81 (0.95–3.48) | 6.50 (2.42–17.45) | 6.11 (3.03–12.32) |
Mental health | |||
Presence of depressive symptoms (CESD-10) | 3.77 (2.47–5.77) | 4.60 (2.76–7.66) | 5.51 (3.52–8.60) |
Presence of depressive symptoms (MHI) | 3.02 (1.94–4.70) | 5.63 (3.10–10.25) | 5.77 (3.57–9.32) |
Physical health | |||
\(\ge \)3 chronic diseases | 1.51 (1.01–2.27) | 1.28 (0.83–1.97) | 1.99 (1.32–3.00) |
Hospital admission past 12 months | 2.35 (1.52–3.62) | 2.03 (1.23–3.35) | 1.88 (1.22–2.89) |
Disability status | |||
Any disability | 2.98 (1.92–4.60) | 4.26 (2.49–7.31) | 4.48 (2.87–6.99) |
Hearing | 2.19 (1.17–4.09) | 3.44 (1.30–9.13) | 2.73 (1.42–5.25) |
Speech/language | 1.98 (1.11–3.51) | 3.59 (1.61–7.99) | 3.41 (1.85–6.27) |
Walking | 4.73 (2.86–7.84) | 5.15 (2.46–10.82) | 4.38 (2.64–7.27) |
Dyspnoea | 1.68 (0.23–12.43) | >999.999 (<0.001–>999.999) | 1.50 (0.21–10.93) |
Dementia | 3.97 (1.23–12.84) | >999.999 (<0.001–>999.999) | 8.26 (1.82–37.46) |
Driving status | |||
Current | 1.0 (Ref.) | 1.0 (Ref.) | 1.0 (Ref.) |
Previous | 2.63 (1.50–4.61) | 3.97 (2.31–6.81) | 7.13 (3.79–13.42) |
Never | 3.88 (2.15–6.99) | 8.99 (4.56–17.76) | 10.64 (5.38–21.02) |