Table 2 Association between visual acuity, physical and mental health indices and the presence of ADL impairment in nAMD patients.

From: Prevalence and risk factors for impaired activities of daily living in patients with neo-vascular age-related macular degeneration who present for anti-VEGF treatment

 

ADL scores

 

Impaired BADLs

Age/sex adjusted OR (95% CI)

Impaired IADLs

Age/sex adjusted OR (95% CI)

Impaired total ADLs

Age/sex adjusted OR (95% CI)

Visual acuity

   

- Normal VA (>20/40)

1.0 (Ref.)

1.0 (Ref.)

1.0 (Ref.)

- Mild VI (\(\le \)20/40 to >20/80)

1.29 (0.77–2.18)

1.77 (1.05–2.98)

1.75 (1.03–3.00)

- Moderate VI (\(\le \)20/80 to >20/200)

3.34 (1.89–5.90)

5.28 (2.52–11.07)

6.22 (3.42–11.31)

- Legally blind (\(\le \)20/200)

1.81 (0.95–3.48)

6.50 (2.42–17.45)

6.11 (3.03–12.32)

Mental health

   

Presence of depressive symptoms (CESD-10)

3.77 (2.47–5.77)

4.60 (2.76–7.66)

5.51 (3.52–8.60)

Presence of depressive symptoms (MHI)

3.02 (1.94–4.70)

5.63 (3.10–10.25)

5.77 (3.57–9.32)

Physical health

   

\(\ge \)3 chronic diseases

1.51 (1.01–2.27)

1.28 (0.83–1.97)

1.99 (1.32–3.00)

Hospital admission past 12 months

2.35 (1.52–3.62)

2.03 (1.23–3.35)

1.88 (1.22–2.89)

Disability status

   

Any disability

2.98 (1.92–4.60)

4.26 (2.49–7.31)

4.48 (2.87–6.99)

Hearing

2.19 (1.17–4.09)

3.44 (1.30–9.13)

2.73 (1.42–5.25)

Speech/language

1.98 (1.11–3.51)

3.59 (1.61–7.99)

3.41 (1.85–6.27)

Walking

4.73 (2.86–7.84)

5.15 (2.46–10.82)

4.38 (2.64–7.27)

Dyspnoea

1.68 (0.23–12.43)

>999.999 (<0.001–>999.999)

1.50 (0.21–10.93)

Dementia

3.97 (1.23–12.84)

>999.999 (<0.001–>999.999)

8.26 (1.82–37.46)

Driving status

   

Current

1.0 (Ref.)

1.0 (Ref.)

1.0 (Ref.)

Previous

2.63 (1.50–4.61)

3.97 (2.31–6.81)

7.13 (3.79–13.42)

Never

3.88 (2.15–6.99)

8.99 (4.56–17.76)

10.64 (5.38–21.02)

  1. Bold values indicate statistical significance p < 0.05.
  2. BADLs basic activities of daily living, IADLs instrumental activities of daily living, ADLs activities of daily living, OR odds ratio, CI confidence interval, CESD-10 Centre of Epidemiology Studies Depression-10 scale, MHI Mental Health Index.