Table 2 Quantitative metrics for retinal perfusion, FAZ and choriocapillaris (CC).
OCTA metrics | No DR (n = 176) | Mild NPDR (n = 160) | Moderate NPDR (n = 98) | Severe NPDR (n = 11) | PDR with PRP (n = 41) | PDR without PRP (n = 12) | Total (n = 498) | p-trend |
|---|---|---|---|---|---|---|---|---|
CC flow voids density, % | ||||||||
All | 17.06 (0.114) | 17.41 (0.118) | 17.60 (0.152) | 17.62 (0.458) | 18.05 (0.234) | 18.41 (0.437) | 17.41 (1.53) | 0.0004 |
>200 μm2 | 15.38 (0.104) | 15.78 (0.108) | 16.01 (0.139) | 16.24 (0.419) | 16.42 (0.214) | 16.88 (0.399) | 15.77 (1.41) | <0.0001 |
>400 μm2 | 12.92 (0.116) | 13.39 (0.12) | 13.68 (0.154) | 14.06 (0.464) | 14.16 (0.237) | 14.67 (0.443) | 13.39 (1.58) | <0.0001 |
>600 μm2 | 10.99 (0.126) | 11.51 (0.131) | 11.82 (0.168) | 12.23 (0.506) | 12.4 (0.258) | 12.99 (0.483) | 11.51 (1.72) | <0.0001 |
>800 μm2 | 9.46 (0.132) | 10.03 (0.137) | 10.36 (0.176) | 10.71 (0.53) | 11.05 (0.271) | 11.52 (0.505) | 10.03 (1.81) | <0.0001 |
Superficial FAZ | ||||||||
Area, mm2 | 0.32 (0.013) | 0.39 (0.013) | 0.41 (0.017) | 0.40 (0.051) | 0.41 (0.026) | 0.52 (0.049) | 0.38 (0.17) | 0.0027 |
Perimeter, mm | 1.34 (0.024) | 1.44 (0.025) | 1.46 (0.032) | 1.33 (0.096) | 1.49 (0.049) | 1.66 (0.092) | 3.03 (1.08) | 0.739 |
Circularity | 2.67 (0.079) | 3.15 (0.082) | 3.26 (0.105) | 2.94 (0.317) | 3.32 (0.162) | 4.18 (0.303) | 1.42 (0.32) | 0.0001 |
Deep FAZ | ||||||||
Area, mm2 | 1.48 (0.056) | 1.71 (0.057) | 1.8 (0.074) | 2.28 (0.222) | 1.85 (0.114) | 2.08 (0.212) | 1.68 (0.74) | 0.0022 |
Perimeter, mm | 1.64 (0.051) | 1.62 (0.053) | 1.55 (0.067) | 1.23 (0.203) | 1.43 (0.104) | 1.44 (0.194) | 7.02 (3.25) | 0.0012 |
Circularity | 6.91 (0.248) | 7.28 (0.257) | 7.02 (0.33) | 6.4 (0.996) | 6.66 (0.508) | 6.88 (0.95) | 1.59 (0.67) | 0.6248 |
SCP_LV_PD, % | 7.46 (0.111) | 8.06 (0.115) | 8.62 (0.147) | 8.85 (0.443) | 8.52 (0.226) | 8.87 (0.423) | 8.03 (1.52) | <0.0001 |
SCP_noLV_PD, % | 19.15 (0.208) | 18.4 (0.216) | 17.17 (0.277) | 17 (0.835) | 16.84 (0.426) | 19.15 (0.208) | 18.08 (0.12) | <0.0001 |
SCP_PD, % | 26.63 (0.15) | 26.27 (0.155) | 25.55 (0.199) | 25.94 (0.6) | 25.3 (0.306) | 25.2 (0.572) | 11.41 (2.64) | 0.1646 |
SCP_LV_VD, % | 3.6 (0.046) | 3.8 (0.048) | 4.02 (0.061) | 4.34 (0.185) | 4.12 (0.094) | 4.24 (0.176) | 3.82 (0.63) | 0.2636 |
SCP_noLV_VD, % | 15.89 (0.206) | 15.08 (0.213) | 13.93 (0.274) | 13.14 (0.826) | 13.41 (0.421) | 12.95 (0.787) | 14.81 (0.13) | 0.0517 |
SCP_VD, % | 19.63 (0.177) | 18.98 (0.183) | 18.06 (0.235) | 17.6 (0.707) | 17.66 (0.361) | 17.36 (0.675) | 18.85 (2.42) | 0.0239 |
DCP _PD, % | 9.52 (0.181) | 8.54 (0.188) | 7.83 (0.241) | 8.47 (0.727) | 7.96 (0.371) | 8.34 (0.693) | 8.69 (2.45) | 0.0754 |
DCP_ VD, % | 8.69 (0.172) | 7.75 (0.179) | 7.04 (0.229) | 7.28 (0.691) | 7.08 (0.353) | 7.24 (0.659) | 7.87 (2.34) | 0.0003 |
