Table 3 Sub-group analysis between severe NPDR and PDR.

From: Flow and ischemic changes in retina and choroid across diabetic retinopathy spectrum: a SS-OCTA study

OCTA metrics

Severe NPDR N = 11

PRP done N = 41

No PRP N = 12

P value PRP vs. PDR without PRP

P value Severe NPDR vs. PRP

P value Severe NPDR vs. w/o PRP

CC flow voids density, %

 All

17.37 (1.53)

18.07 (1.45)

18.20 (1.65)

0.5217

0.1178

0.1335

 >200 μm2

16.00 (1.65)

16.44 (1.58)

16.67 (1.59)

0.6611

0.4142

0.3287

 >400 μm2

13.78 (1.83)

14.18 (1.96)

14.44 (1.81)

0.5636

0.3074

0.3927

 >600 μm2

11.90 (1.93)

12.42 (2.16)

12.72 (2.01)

0.6071

0.3074

0.3293

 >800 μm2

10.33 (1.98)

11.08 (2.24)

11.21 (2.14)

0.7932

0.2299

0.3205

Superficial FAZ

 Area, mm2

0.297

0.6899

0.2875

0.297

0.6899

0.2875

 Perimeter, mm

2.88 (0.65)

3.33 (0.93)

4.13 (1.93)

0.0795

0.2137

0.0056

 Circularity

1.31 (0.29)

1.49 (0.38)

1.64 (0.38)

0.1142

0.1602

0.0036

Deep FAZ

 Area, mm2

2.26 (0.62)

1.85 (0.69)

2.07 (0.87)

0.3672

0.0779

0.5452

 Perimeter, mm

6.12 (1.99)

6.68 (2.78)

6.65 (1.75)

0.3599

0.583

0.2351

 Circularity

1.17 (0.35)

1.44 (0.57)

1.39 (0.50)

0.7932

0.1348

0.5658

 SCP_PD

13.35 (2.17)

11.05 (1.91)

11.98 (1.91)

0.1433

0.0017

0.0268

 SCP_ LV_PD

8.66 (1.01)

8.53 (1.44)

8.72 (1.15)

0.9749

0.9121

0.8934

 SCP_noLV_PD

7.83 (1.96)

6.06 (2.00)

6.73 (1.75)

0.1532

0.0055

0.1693

 SCP_VD

11.10 (1.79)

9.41 (1.88)

10.06 (1.86)

0.2964

0.0029

0.2115

 SCP_noLV_VD

7.51 (1.77)

6.13 (1.99)

6.64 (1.72)

0.2332

0.0099

0.2414

 DCP_PD

8.78 (1.78)

7.93 (2.44)

8.59 (1.93)

0.398

0.2896

0.8088

 DCP_VD

7.53 (1.50)

7.06 (2.23)

7.46 (1.64)

0.567

0.507

0.9075

  1. SCP Superficial Capillary Plexus, DCP Deep Capillary Plexus, VD Vessel Density, PD Perfusion Density, LV large vessels, no_LV without large vessels.
  2. The p values that are statistically significant (p < 0.05) are bolded.