Table 2 Multivariate analysis of systemic and ocular features associated with diabetic macular oedema treatment.
HR | 95% CI | p-value | |
|---|---|---|---|
Systemic features | |||
BMI, kg/m2 | 0.99 | 0.96–1.02 | 0.390 |
Systolic blood pressure, mmHg | 1.00 | 1.00–1.01 | 0.542 |
Diastolic blood pressure, mmHg | 1.00 | 0.99–1.02 | 0.686 |
Creatinine, μmol/L | 1.00 | 1.00–1.00 | 0.223 |
LDL cholesterol, mmol/L | 1.03 | 0.90–1.18 | 0.646 |
HbA1c, % | 0.95 | 0.89–1.01 | 0.104 |
Diabetic maculopathy feature | |||
Haemorrhages within inner zone with VA 6/12 or worse | 12.00 | 5.54–25.95 | <0.001 |
Hard exudates within inner zone | 7.36 | 3.44–15.75 | <0.001 |
Hard exudates within outer zone | 1.98 | 0.75–5.22 | 0.165 |
Haemorrhages within outer zone with VA 6/12 or worse | 1.29 | 0.33–5.01 | 0.712 |
Haemorrhages within inner zone with VA better than 6/12 | 0.58 | 0.22–1.55 | 0.278 |
Haemorrhages within inner zone with VA better than 6/12 (on repeat screening) | 0.50 | 0.06–4.18 | 0.525 |
Haemorrhages within outer zone with VA better than 6/12* | 1.00 | ||
Diabetic retinopathy status | |||
Proliferative DR | 7.63 | 4.00–14.56 | <0.001 |
Severe non-proliferative DR | 10.10 | 6.00–17.02 | <0.001 |
Moderate non-proliferative DR | 5.42 | 3.27–8.99 | <0.001 |
Mild non-proliferative DR* | 1.00 | ||