Table 2 Multivariate analysis of systemic and ocular features associated with diabetic macular oedema treatment.

From: Predicting the need for diabetic macular oedema treatment from photographic screening in the Singapore Integrated Diabetic Retinopathy Programme (SiDRP)

 

HR

95% CI

p-value

Systemic features

 BMI, kg/m2

0.99

0.96–1.02

0.390

 Systolic blood pressure, mmHg

1.00

1.00–1.01

0.542

 Diastolic blood pressure, mmHg

1.00

0.99–1.02

0.686

 Creatinine, μmol/L

1.00

1.00–1.00

0.223

 LDL cholesterol, mmol/L

1.03

0.90–1.18

0.646

 HbA1c, %

0.95

0.89–1.01

0.104

Diabetic maculopathy feature

 Haemorrhages within inner zone with VA 6/12 or worse

12.00

5.54–25.95

<0.001

 Hard exudates within inner zone

7.36

3.44–15.75

<0.001

 Hard exudates within outer zone

1.98

0.75–5.22

0.165

 Haemorrhages within outer zone with VA 6/12 or worse

1.29

0.33–5.01

0.712

 Haemorrhages within inner zone with VA better than 6/12

0.58

0.22–1.55

0.278

 Haemorrhages within inner zone with VA better than 6/12 (on repeat screening)

0.50

0.06–4.18

0.525

 Haemorrhages within outer zone with VA better than 6/12*

1.00

  

Diabetic retinopathy status

 Proliferative DR

7.63

4.00–14.56

<0.001

 Severe non-proliferative DR

10.10

6.00–17.02

<0.001

 Moderate non-proliferative DR

5.42

3.27–8.99

<0.001

 Mild non-proliferative DR*

1.00

  
  1. HR Hazard ratio, CI confidence interval, BMI body mass index, LDL low-density lipoprotein, VA visual acuity, DR diabetic retinopathy
  2. *Reference group.