Table 1 Demographic information of phentermine and overweight cohorts after Propensity Score Matching.

From: Lower incidence of diabetic retinopathy and worsening events after phentermine assisted weight loss across a large U.S. cohort

Variable

Phentermine [SD] or (%) (N = 26,611)

Overweight [SD] or (%) (N = 26,611)

Standard difference

Age (years)

50.3 ± 13.2

50.3 ± 13.6

0.007

Gender

 Female

18,944 (71.189%)

18,757 (70.486%)

0.016

 Male

6876 (25.839%)

7064 (26.545%)

0.016

Race

 White

14,565 (54.733%)

14,589 (54.823%)

0.002

 Black

5838 (21.938%)

5796 (21.78%)

0.004

Ethnicity

 Hispanic or Latino

4135 (15.539%)

4109 (15.441%)

0.003

BMI

39.8 ± 8.4

36.3 ± 7.5

0.439

Systemic Diagnoses

 Essential HTN

15,741(59.2%)

15,601 (58.6%)

0.011

 Type 1 DM

1464 (5.5%)

1347 (5.1%)

0.020

 Type II DM

15,114 (56.8%)

15,071 (56.6%)

0.003

 Long term use of insulin

2169 (8.2%)

2053 (7.7%)

0.016

 Hypercholesterolemia

4254 (16.0%)

4156 (15.6%)

0.010

 CAD

1923 (7.2%)

1893 (7.1%)

0.004

Baseline DR

 Type 1 DM w/ Mild NPDR

33 (0.1%)

10 (0.0%)

0.030

 Type 2 DM w/ Mild NPDR

207 (0.8%)

161 (0.6%)

0.021

 Type 1 DM w/ Moderate NPDR

10 (0.0%)

10 (0.0%)

<0.001

 Type 2 DM w/ Moderate NPDR

50 (0.2%)

37 (0.1%)

0.012

 Type 1 DM w/ Severe NPDR

10 (0.0%)

10 (0.0%)

<0.001

 Type 2 DM w/ Severe NPDR

29 (0.1%)

12 (0.0%)

0.023

 Type 1 DM w/ PDR

23 (0.1%)

10 (0.0%)

0.020

 Type 2 DM w/ PDR

78 (0.3%)

46 (0.2%)

0.025

Laboratory Values

 Hemoglobin A1c

6.6 ± 1.7

7.2 ± 2.0

0.305

 Serum Cholesterol

178.0 ± 47.8

180.8 ± 49.0

0.058

  1. SD standard deviation, BMI body mass index, HTN hypertension,
  2. DM diabetes mellitus, CAD coronary artery disease.