Table 2 Risk of diabetic retinopathy and complications after phentermine treatment.
Cohorts | Patients in cohort | Patients with outcome | Risk ratio (95% CI) | P value |
|---|---|---|---|---|
Mild non-proliferative diabetic retinopathy | ||||
Phentermine | 26,370 | 152 | 0.621 (0.508, 0.760) | <0.001 |
Overweight | 26,406 | 245 | ||
Moderate non-proliferative diabetic retinopathy | ||||
Phentermine | 26,551 | 51 | 0.567 (0.402, 0.799) | 0.001 |
Overweight | 26,559 | 90 | ||
Severe non-proliferative diabetic retinopathy | ||||
Phentermine | 26,577 | 11 | 0.479 (0.233, 0.981) | 0.040 |
Overweight | 26,591 | 23 | ||
Proliferative diabetic retinopathy | ||||
Phentermine | 26,514 | 50 | 0.451 (0.323, 0.629) | <0.001 |
Overweight | 26,531 | 111 | ||
Diabetic retinopathy with macular edema | ||||
Phentermine | 26,261 | 119 | 0.462 (0.372, 0.573) | <0.001 |
Overweight | 26,276 | 258 | ||
Vitreous hemorrhage | ||||
Phentermine | 26,561 | 17 | 0.347 (0.200, 0.602) | <0.001 |
Overweight | 26,564 | 49 | ||
Intravitreal anti-VEGF injection | ||||
Phentermine | 26,556 | 36 | 0.530 (0.354, 0.793) | 0.002 |
Overweight | 26,563 | 68 | ||
Pars plana vitrectomy | ||||
Phentermine | 26,593 | 11 | 0.786 (0.357, 1.731) | 0.549 |
Overweight | 26,595 | 14 | ||
Pan retinal photocoagulation | ||||
Phentermine | 26,584 | 12 | 0.546 (0.270, 1.102) | 0.086 |
Overweight | 26,590 | 22 | ||
Tractional retinal detachment | ||||
Phentermine | 26,598 | 10 | 0.588 (0.269, 1.284) | 0.178 |
Overweight | 26,589 | 17 | ||
