Fig. 1: Sema3A and VEGF signalling via Nrp1 in angiogenesis and vascular permeability in DR.

Created using information from Joyal et al. [17], Raimondi et al. [18], Goldman et al. [19] and Ochsenbein et al. [20]. DR diabetic retinopathy, Nrp1 neuropilin 1, Sema3A semaphorin 3A, VEGF vascular endothelial growth factor, VEGFR2 VEGF receptor 2.