Fig. 4: Transmission electron microscopy of an explanted Descemet-Endothelium complex of a recipient’s eye with Fuchs Endothelial Corneal Dystrophy, which showed intraoperative splitting during Descemetorhexis.

*Lamellar split layer of Descemet Membrane. Anterior = Anterior side of the Descemet-Endothelium complex. Posterior = Posterior side of the Descemet-Endothelium complex. IFM Interfacial matrix, ABL Anterior banded layer, PNBL Posterior non-banded layer. a Cross-sectional view of a region with lamellar splitting without rupture of the split layer. The thickness of the split layer is about 2 µm. b Cross-sectional view of a region with lamellar splitting with rupture of the split section. The thickness of the split layer is about 2 µm. c Magnification of panel (b) showing the irregular border of the split layer.