Table 1 Summary of included studies.

From: Association between metabolic syndrome and cataract: a meta-analysis

Study

Country

Design

Participants

Sample size

Mean age (years)

Men (%)

Diagnostic criteria of MetS

No. of patients with MetS

Follow-up duration for cohort studies (years)

Methods for the diagnosis of cataract

Type of cataract

Number of patients with cataract

Variables adjusted

Paunksnis [18]

Lithuania

CS

Community people aged 35–64 years

1282

50

44.7

NCEP-ATP III

294

NA

Ophthalmologic examination

Overall cataract

236

Age and sex

Lindblad [19]

Sweden

PC

Community women aged 49–83 years

35,369

62.1

0

IDF

124

8.2

ICD-10 codes

Cataract surgery

4508

Age, smoking, alcohol consumption, use of steroid medication, use of vitamin supplement and educational level

Galeone [20]

Italy

CC

Hospitalized patients for acute, non-neoplastic conditions

2283

62

47

IDF

147

NA

Ophthalmologic examination

Cataract surgery

761

Age, sex, and study centre

Sabanayagam [21]

Singapore

CS

Community people aged 40–80 years

2794

58.2

48.3

NCEP-ATP III

1194

NA

Ophthalmologic examination

Overall cataract

1268

Age, sex, education, and smoking status

Maralani [22]

Australia

PC

Community people aged 35 years or older

1997

63.9

42.3

IDF

246

10

Ophthalmologic examination

Overall cataract

857

Age, sex, eye disease at baseline, preexisting DM, CAD, and stroke, and family history of blindness

Park [23]

Korea

CS

Community people aged 40 years or older

11,076

56

43.1

NCEP-ATP III

4364

NA

Ophthalmologic examination

Overall cataract

5406

Age, sex, income, education, residential area, smoking status, drinking alcohol, exercise, occupation, family history of eye disease, and sun exposure

Lindblad [24]

Sweden

PC

Community men aged 45–79 years

45,049

59.2

100

IDF

880

15

ICD-10 codes

Cataract surgery

7573

Age, smoking, alcohol consumption, steroid medication use, vitamin supplement use, educational level, and physical activity

Jee [25]

Korea

CS

Community people aged 50–77 years

40,262

57.9

47.7

NCEP-ATP III

6971

NA

Self-reported clinically diagnosed cataract

Overall cataract

1972

Age, sex, residence area, BMI, and energy intake

Chang [26]

Taiwan

CS

Community people aged 31–77 years

121,380

49.9

35.9

NCEP-ATP III

34,817

NA

Self-reported clinically diagnosed cataract

Overall cataract

17,320

Age, sex, smoking, alcohol drinking, exercise, HGB, TC, LDL-C, eGFR, and UA

Xu [27]

UK

PC

Community people aged 40–69 years

117,972

56.5

50

NCEP-ATP III

32,092

11

ICD-10 codes

Overall cataract

4172

Age, sex, ethnicity, education, SES, smoking, alcohol drinking, and sun exposure

  1. MetS metabolic syndrome, CS cross-sectional, PC prospective cohort, CC case-control, IDF International Diabetes Federation, NCEP-ATP III National Cholesterol Education Program Adult Treatment Panel III, NA not applicable, ICD-10 International Classification of Disease Tenth Edition, DM diabetes mellitus, CAD coronary artery disease, HGB haemoglobin, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR estimated glomerular filtrating rate, UA uric acid, SES socioeconomic status.