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Splendore–Hoeppli phenomenon in vernal keratoconjunctivitis: a rare photographic documentation in a paediatric case

Eye (2025)Cite this article

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Yellowish-white elevated paralimbal nodules on the superior bulbar conjunctiva (eosinophilic proteinaceous deposits)represent the Splendore–Hoeppli phenomenon.

Teaching Point: Recognition of the Splendore–Hoeppli phenomenon in VKC offers a distinctive, non-invasive diagnostic clue.

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Authors and Affiliations

  1. JPM Rotary Eye Hospital, Cuttack, Odisha, India

    Shweta Dhiman, Raj Vaishal Kenia & Saumya Ota

Authors
  1. Shweta Dhiman
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  2. Raj Vaishal Kenia
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  3. Saumya Ota
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Contributions

SD contributed to case diagnosis and image acquisition. RVK conceptualized the photo essay, performed the literature review, and prepared the manuscript. SO assisted in data interpretation and manuscript preparation. All authors approved the final version of the manuscript.

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Correspondence to Raj Vaishal Kenia.

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The authors declare no competing interests.

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Dhiman, S., Kenia, R.V. & Ota, S. Splendore–Hoeppli phenomenon in vernal keratoconjunctivitis: a rare photographic documentation in a paediatric case. Eye (2025). https://doi.org/10.1038/s41433-025-04037-0

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  • DOI: https://doi.org/10.1038/s41433-025-04037-0

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