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The unseen danger: cumulative laser-induced maculopathy from indirect exposure during cat play

Eye (2025)Cite this article

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Fig. 1: Fundus and multimodal imaging of a 30-year-old female who developed progressive bilateral vision loss after 1-month repeated indirect exposure to a handheld Class 3B red laser pointer (650 nm, 198 mW) during cat play.

Acknowledgements

We thank the patients for granting permission to publish this information. We thank Prof. Xiaodong Sun (Shanghai General Hospital) for his valuable suggestions throughout the study.

Funding

This work was supported by the National Natural Science Foundation of China (82571246) and Shanghai “Rising Stars of Medical Talents” Youth Development Program (SHWSRS(2025)_071). There are no conflicts of interest for the other authors.

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Authors and Affiliations

  1. Department of Ophthalmology, Shanghai General Hospital (Shanghai First People’s Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China

    Haoliang Zhang, Tong Li & Yuanyuan Gong

  2. National Clinical Research Center for Ophthalmic Diseases, Shanghai, China

    Haoliang Zhang, Tong Li & Yuanyuan Gong

  3. Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, China

    Tong Li & Yuanyuan Gong

  4. Shanghai Key Laboratory of Fundus Diseases, Shanghai, China

    Tong Li & Yuanyuan Gong

  5. Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Disease, Shanghai, China

    Yuanyuan Gong

Authors
  1. Haoliang Zhang
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  2. Tong Li
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  3. Yuanyuan Gong
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Contributions

Concept and design: H. Zhang, Y. Gong. Acquisition, analysis, or interpretation of data: H. Zhang. T. Li. Drafting of the manuscript: H. Zhang, T. Li. Critical revision of the manuscript for important intellectual content: T. Li, Y. Gong. Supervision: T. Li, Y. Gong.

Corresponding author

Correspondence to Tong Li.

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Competing interests

T.L.: Consultant—Innostellar Biotherapeutics.

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Zhang, H., Li, T. & Gong, Y. The unseen danger: cumulative laser-induced maculopathy from indirect exposure during cat play. Eye (2025). https://doi.org/10.1038/s41433-025-04149-7

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  • DOI: https://doi.org/10.1038/s41433-025-04149-7

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