Table 1 Demographic and clinical characteristics of participants in two groups at baseline and final visit.

From: Drugs with meibomian gland expression alone versus combined with intense pulsed light in ocular rosacea: a randomised controlled study

 

IPL-MGX with erythromycin ointment

MGX with erythromycin ointment

 

Baseline

Final visit

Baseline

Final visit

Median age (IQR), years

38 (31–44)

Gender n (%)

Female

40 (83%)

Male

8 (17%)

Median OSDI score (IQR)

20.83 (10.42–37.50)

8.33 (2.08–20.31)

21.88 (10.42–39.06)

10.42 (2.08–21.88)

Upper lid margin telangiectasia grade, n (%)

 0

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 1

1 (2%)

4 (8%)

5 (10%)

2 (4%)

 2

15 (31%)

18 (38%)

12 (25%)

15 (31%)

 3

32 (67%)

26 (54%)

31 (65%)

31 (65%)

Lower lid margin telangiectasia grade, n (%)

 0

0 (0%)

1 (2%)

0 (0%)

0 (0%)

 1

7 (15%)

10 (21%)

7 (15%)

8 (17%)

 2

18 (38%)

28 (58%)

20 (42%)

19 (40%)

 3

23 (48%)

9 (19%)

21 (44%)

21 (44%)

Median ML score (IQR)

 Upper eyelid (u-ML)

2 (0–5)

2 (0–5)

2(0–5)

2(0–5)

 Lower eyelid (l-ML)

3 (0–6)

3 (0–6)

3(0–6)

2(0–6)

 Amount of D. folliculorum

0 (0–2)

0 (0–0)

0 (0–2)

0 (0–0)

Detection of demodex, n (%)

 Positivea

8 (17%)

7 (15%)

8 (17%)

6 (13%)

 Negativeb

40 (83%)

41 (85%)

40 (83%)

42 (88%)

Mean MGYSS ± SD

 Upper eyelid (u-MGYSS)

15 ± 5.7

26 ± 8.1

15 ± 6.2

19 ± 7.4

 Lower eyelid (l-MGYSS)

16 ± 6.3

26 ± 7.2

17 ± 6.3

20 ± 6.2

 Total (t-MGYSS)

31 ± 10.6

52 ± 14.2

32 ± 11.6

39 ± 12.5

Meibography score, n (%)

 0

0 (0%)

1 (2%)

0 (0%)

0 (0%)

 1

1 (2%)

0 (0%)

0 (0%)

0 (0%)

 2

22 (46%)

24 (50%)

23 (48%)

26 (54%)

 3

6 (13%)

6 (13%)

5 (10%)

4 (8%)

 4

14 (29%)

12 (25%)

13 (27%)

10 (21%)

 5

1 (2%)

1 (2%)

3 (6%)

3 (6%)

 6

4 (8%)

4 (8%)

4 (8%)

5 (10%)

Median TBUT (IQR), s

3.68 (2.95–4.27)

4.24 (3.63–5.57)

3.64 (3.22–4.31)

3.84 (3.03–4.76)

Median CFS score (IQR)

2 (1–4)

2 (0–3)

2 (0–4)

3 (1–4)

Schirmer’s test value (IQR), mm

15 (7–30)

14 (8–24)

15 (9–25)

14 (9–23)

Schirmer’s test, n (%)

 ≥10 mm/5 min

32 (67%)

35 (73%)

36 (75%)

35 (73%)

 <10 mm/5 min

16 (33%)

13 (27%)

12 (25%)

13 (27%)

  1. IPL intense pulsed light, MGX meibomian gland expression, OSDI ocular surface disease index, IQR interquartile range, ML Marx line, MGYSS meibomian gland yield secretion score, TBUT tear break-up time, CFS corneal fluorescein staining.
  2. aRefers to the presence of ≥3 mites on the 3 lashes of an eyelid.
  3. bRefers to the presence of <3 mites on the 3 lashes of an eyelid.
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