Table 1 Baseline characteristics before and after propensity score matching (No. [%]).
From: Unmasking an ocular risk: keratoconus in atopic dermatitis patients treated with dupilumab
Before Matching | After Matching | |||||
|---|---|---|---|---|---|---|
Characteristic Name | Dupilumab Cohort | Control Cohort | Standardised | Dupilumab Cohort | Control Cohort | Standardised |
(n = 39,287) | (n = 709,749) | Mean Differencea | (n = 39,285) | (n = 39,285) | Mean Differencea | |
Age at Index, Mean ± Standard Deviation | 34.5 ± 24.6 | 21.8 ± 24.8 | 0.5105 | 34.5 ± 24.6 | 34.6 ± 24.8 | 0.0047 |
Gender (%) | ||||||
Male | 45.86% | 44.53% | 0.0268 | 45.86% | 45.66% | 0.004 |
Female | 52.67% | 53.64% | 0.0194 | 52.67% | 52.86% | 0.0039 |
Race (%) | ||||||
White | 51.00% | 44.59% | 0.1286 | 51.00% | 51.22% | 0.0044 |
Black or African American | 21.16% | 23.15% | 0.0479 | 21.16% | 21.21% | 0.0011 |
Asian | 9.21% | 8.09% | 0.0396 | 9.21% | 9.21% | 0.0001 |
Native Hawaiian or Other Pacific Islander | 0.73% | 0.85% | 0.0134 | 0.73% | 0.71% | 0.003 |
American Indian or Alaska Native | 0.66% | 0.60% | 0.0078 | 0.66% | 0.64% | 0.0022 |
Other Race | 5.13% | 7.61% | 0.1017 | 5.13% | 5.01% | 0.0057 |
Unknown Race | 12.10% | 15.10% | 0.0875 | 12.10% | 12.01% | 0.003 |
Ethnicity (%) | ||||||
Hispanic or Latino | 8.24% | 12.58% | 0.1426 | 8.24% | 8.08% | 0.006 |
Not Hispanic or Latino | 68.00% | 58.58% | 0.1962 | 67.99% | 68.05% | 0.0013 |
Unknown Ethnicity | 23.77% | 28.84% | 0.1153 | 23.77% | 23.87% | 0.0025 |
Comorbidities (%) | ||||||
Conjunctivitis | 13.39% | 12.55% | 0.025 | 13.39% | 13.08% | 0.0091 |
Allergies | 7.07% | 3.32% | 0.1694 | 7.06% | 6.86% | 0.0078 |
Dry eye syndrome | 4.22% | 2.68% | 0.0849 | 4.22% | 3.84% | 0.0195 |
Systemic connective tissue disorders | 3.08% | 1.48% | 0.1071 | 3.07% | 2.66% | 0.0249 |
Localised connective tissue disorders | 1.11% | 0.64% | 0.0512 | 1.11% | 0.85% | 0.0272 |
Down syndrome | 0.10% | 0.19% | 0.025 | 0.10% | 0.09% | 0.0034 |
Visits (%) | ||||||
Ophthalmology Visits | 11.46% | 7.73% | 0.1269 | 11.46% | 11.24% | 0.0068 |
