Fig. 3: Sankey diagram illustrating the transition of retinal phenotypes from baseline to final assessment.

The left column represents the baseline epiretinal membrane-foveoschisis (ERM-F) subtypes: open-flat (76/124 eyes), open-elevated (30/124 eyes), and closed (18/124 eyes). The right column displays the final phenotypes: open-flat (58/124 eyes), open-elevated (35/124 eyes), closed (12/124 eyes), mixed ERM-F/lamellar macular hole (LMH) (14/124 eyes), LMH (3/124 eyes), and normal foveal morphology (2/124 eyes). Two eyes progressed from open-flat via mixed ERM-F/LMH to full-thickness macular hole (FTMH) during follow-up; FTMH is shown as a separate terminal branch for illustration but was treated as a censoring event and not included in final subtype counts. The flow widths between baseline and final subtypes are proportional to the number of eyes transitioning between phenotypes, highlighting changes and stability in retinal conditions over time. Figure created using SankeyMATIC (sankeymatic.com).