Fig. 3
From: GDNF-mediated rescue of the nigrostriatal system depends on the degree of degeneration
GDNF-F-DD leads to partial recovery of motor impairment when there is an ongoing nigrostriatal degeneration. a Amphetamine-induced rotations measured 7, 14, and 19 weeks after 6-OHDA lesion (n = 8–10 per group). One-way ANOVA with Tukey multiple comparison tests performed on week 19. Repeated-measures ANOVA with Tukey multiple comparison tests performed on weeks 7, 14, and 19 was statistically significant in the Rescue group. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.0001. b Correlation between numbers of TH neurons and amphetamine-induced rotations on week 19. c Correlation between numbers of VMAT2 neurons and amphetamine-induced rotations on week 19. d Correlation between numbers of pRPS6 neurons and amphetamine-induced rotations on week 19
