Fig. 5: Efficiency of GNPs in the delivery of DNAzyme into HeLa cells. | Gene Therapy

Fig. 5: Efficiency of GNPs in the delivery of DNAzyme into HeLa cells.

From: Natural polyphenol assisted delivery of single-strand oligonucleotides by cationic polymers

Fig. 5: Efficiency of GNPs in the delivery of DNAzyme into HeLa cells.The alternative text for this image may have been generated using AI.

a Schematic illustration of Bcl-2 DNAzyme delivery by GNPs. b Bcl-2 mRNA expression in GNPs-treated HeLa cells for 24 h. Results represent three independent biological PCR reactions performed in triplicate. c Representative Bcl-2 protein expressions in the treated cells. d Flow cytometry analysis of treated HeLa cells stained by annexin V and propidium iodide. The concentration of DNAzyme in each well fixed at 100 nM (0.8 μg), the dose of EGCG and PLL in each well was both 5.0 μg. The doses of TE and LPF were 2.0 μL. **p < 0.01, ***p < 0.001 analyzed by Student’s t test.

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