Fig. 5: Analysis of retrograde transport in the motor (M1–M2) and somatosensory (S1–S2) cortical areas. | Gene Therapy

Fig. 5: Analysis of retrograde transport in the motor (M1–M2) and somatosensory (S1–S2) cortical areas.

From: Maximizing lentiviral vector gene transfer in the CNS

Fig. 5

a Coronal sections showing the retrograde transport of LV-FuG/B2 PGK-GFP reporter from the injection site (see needle) along the entire anterior-posterior axis. b Motor and somatosensory cortical cell bodies were quantified from +1.18 to −0.70 mm from the bregma within illustrated subareas described in the Paxinos Atlas. c Total infected cell bodies in the motor and somatosensory areas of three mice. d Detailed quantification of infected cell bodies within the motor and somatosensory areas of three mice. M1 = primary motor cortex, M2 = secondary motor cortex, S1 = primary somatosensory cortex, S1BF = primary somatosensory cortex, barrel field, S1DZ = primary somatosensory cortex, dysgranular region, S1FL = primary somatosensory cortex, forelimb, S1HL = primary somatosensory cortex, hindlimb, S1J-S1ULp = primary somatosensory cortex, jaw region, and upper lip region, S1ULp = primary somatosensory cortex, upper lip region, S2 = secondary somatosensory cortex.

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