Fig. 6: Fiber size distribution histograms of gastrocnemius (GAS) and tibialis anterior (TA) muscles from Cx32 KO mice at six months post NT-3 gene transfer.
From: AAV1.NT-3 gene therapy for X-linked Charcot–Marie–Tooth neuropathy type 1

Size distribution histograms from both muscles showed a shift to larger diameter subgroups with NT-3 gene therapy compared to untreated Cx32 KO cohort (a b). n = 8 per group. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, Bonferroni’s multiple comparisons test.