Fig. 2: No angiogenesis in AAV2-VEGF-B186 transduced hearts was observed. | Gene Therapy

Fig. 2: No angiogenesis in AAV2-VEGF-B186 transduced hearts was observed.

From: AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses

Fig. 2

The mean capillary area was at the same level in the (a1–a2) AAV2-VEGF-B186 hearts compared to (b1–b2) the control group. c1–c2 There was no improvement in myocardial perfusion reserve measured by [15O]H2O-PET. d1–d2 Analysis of [18F]FDG-PET imaging showed no change in FDG uptake at the gene transfer or the infarction area. Results are represented as dot plots separately for each individual animal and as mean ± 95% CI. Scale bar: 100 µm.

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