Fig. 6: Neutralizing antibodies in the pig sera. | Gene Therapy

Fig. 6: Neutralizing antibodies in the pig sera.

From: AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses

Fig. 6

nAbs were measured from eight animals before and after the AAV2 gene transfer. Each graph represents an individual animal. The curves present the capability of the serum anti-AAV2 antibodies to prevent AAV2-muSEAP transduction in 293T cells. The framed combined dot plot shows the serum dilution needed to inhibit AAV2-muSEAP transduction efficacy of more than 50%.

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