Fig. 3: Behavioral tests of lesioned and implanted subjects.

A Timeline of the experimental procedure. B Amphetamine-induced rotation test, one week before the implantation of astrocytes and nine weeks after the transplant; Sham, 6-OHDA + Astrocytes and 6-OHDA lesion + Astrocytes Th groups were compared with a Two-Way ANOVA test and Sidak´s multiple comparisons test was applied as post hoc test, p < 0.05 was considered statistically significant. C Forelimb placement asymmetry test, the basal level before 6-OHDA lesion, four and eight weeks after transplantation. Sham, 6-OHDA + Astrocytes and 6-OHDA lesion + Astrocytes Th groups were compared with a Repeated Measures ANOVA and for the three groups Tukey´s multiple comparison test as post hoc test was used as well as for each temporal determination, p < 0.05 was considered statistically significant. D Inclined beam motor balance test (24 mm width). E Inclined beam motor balance test (18 mm width). Sham, 6-OHDA + Astrocytes and 6-OHDA lesion + Astrocytes Th groups were compared with a Repeated Measures ANOVA and for the three groups Tukey´s multiple comparison test as post hoc test was used as well as for each temporal determination, p < 0.05 was considered statistically significant. Bars represent the Standard error of the mean (SEM), *p < 0.05, n = 4.