Fig. 5: Histological analysis of liver and heart following fetal scAAV9 delivery. | Gene Therapy

Fig. 5: Histological analysis of liver and heart following fetal scAAV9 delivery.

From: Transabdominal ultrasound guided AAV9-GFP delivery in fetal pigs: a translational and minimally invasive model for in utero fetal gene therapy

Fig. 5

a Histological analysis of liver morphology by HE staining and hepatocytes functionality evaluated by PAS activity; Masson Trichrome (MT) analysis did not highlight fibrotic areas in scAAV9-GFP injected fetuses. b Histological analysis of myocardium morphology by HE staining did not reveal significant alterations or inflammatory infiltrations. MT analysis did not highlight fibrotic areas in scAAV9-GFP injected fetuses. Scalebar, 100 μm.

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