Table 3 Number of alleles with count of new mutating positions as compared to the existing databases.

From: Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations

 

IGHV

IGKV

IGLV

Mutation counts

Complete sequence

V region only

Complete sequence

V region only

Complete sequence

V region only

Zero

279

312

85

95

68

91

One

102

72

85

78

102

93

Two

21

19

7

4

26

14

Three

5

5

1

1

3

2

Four

1

1

1

1

1

0

Five

1

1

0

0

0

0

  1. Complete sequence includes leader sequence and the V region for all the V genes. This is important to realize that 98 IGHV, 9 IGKV and 35 IGLV alleles are partial and do not contain the leader sequence.
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