Fig. 3: Heatmap of significant DEGs reveals gene expression clusters.
From: IgE-binding monocytes upregulate the coagulation cascade in allergic horses
A Heatmap was generated to show the expression of each DEG across individuals and at both timepoints. Each column represents a different horse, and samples are ordered healthy (n = 5, gray bars) then allergic (n = 7, orange bars) individuals for each phase. A vertical black line separates the “Remission Phase” (left) and “Clinical Phase” (right). Each row represents a different gene and gene expression is color coded to represent up- (red) or downregulation (blue) compared to the average for that gene. Genes have been grouped editorially to aid visualization of expression patterns: A DEGs in allergic horses at both timepoints, B DEGs in allergic horses only during the “Remission Phase”, and C DEGs in allergic horses only during the “Clinical Phase”. Genes with over +/−2 FC are bolded.
