Table 2 Mean (quartiles) of urinary albumin/creatinine (ACR) at baseline according to IRF5 genotypes and P values of trend tests across genotypes in adjusted linear regression analyses.

From: Genetic variants of interferon-response factor 5 are associated with the incidence of chronic kidney disease: the D.E.S.I.R. study

SNP ID

Urinary ACR (mg/g)

Median (25%-75%)

P (trenda adjusted for sex, age/sex, age, BMI)

MM

Mm

mm

rs4731532

7.01 (4.80–11.96)

7.24 (4.79–11.59)

7.10 (4.87–12.40)

0.88/0.95

rs752637

7.01 (4.75–11.73)

7.30 (4.87–11.91)

7.06 (4.82–11.79)

0.27/0.30

rs3807306

7.05 (4.83–11.57)

7.15 (4.86–11.71)

7.05 (4.78–12.57)

0.88/0.95

rs11761199

7.14 (4.88–11.70)

7.11 (4.81–11.78)

7.02 (4.75–12.1)

0.54/0.44

rs78658945

7.06 (4.79–11.70)

7.16 (4.83–11.96)

7.99 (4.94–12.99)

0.30/0.33

rs79288514

7.08 (4.80–11.79)

7.11 (4.80–11.56)

7.69 (5.05–12.19)

0.70/0.56

rs1874328

7.21 (4.97–11.81)

7.09 (4.80–11.91)

6.85 (4.49–10.96)

0.01/0.01

rs2070197

7.11 (4.79–11.66)

7.04 (4.95–12.72)

6.97 (4.96–11.14)

0.51/0.64

rs10954213

6.99 (4.68–11.78)

7.23 (4.91–11.80)

7.07 (4.94–11.61)

0.21/0.22

rs11770589

6.85 (4.61–11.48)

7.21 (4.89–11.98)

7.05 (4.98–11.7)

0.06/0.07

rs10954214

7.01 (4.73–11.69)

7.29 (4.93–11.91)

7.11 (4.90–11.98)

0.14/0.15

  1. M major allele, m minor allele.
  2. aLinear regression analysis on loge(ACR).
  3. The D.E.S.I.R. study.