Table 1 Clinical and demographic features of Meniere Disease patients.

From: Cytokine profiling and transcriptomics in mononuclear cells define immune variants in Meniere Disease

 

MDH (N = 8)

MDL (N = 34)

p

Sex (% woman) (N)

50% (4)

59% (20)

0.7061

Age (mean ± SD)

58.5 ± 6.6

58.0 ± 14.2

0.8832

Age of onset (mean ± SD)

44.5 ± 13.2

45.02 ± 13.2

0.9208

Years of evolution (mean ± SD)

14.0 ± 10.3

12.9 ± 7.8

0.7852

Laterality (% unilateral) (N)

75% (6)

74% (25)

1.0000

Affected ear (% right) (N)

25 (2)

29 (10)

0.8822

Family history of ear affections (% yes) (N)

38% (3)

59% (20)

0.4330

Family history of MD (% yes) (N)

25% (2)

15% (5)

0.6012

Headache (% yes) (N)

38% (3)

50% (17)

0.6997

Migraine (% yes) (N)

38% (3)

29% (10)

0.6861

History of Autoimmune disease (% yes) (N)

38% (3)

29% (10)

0.6861

Number of crises in last 6 months (mean ± SD)

2.0 ± 3.3

1.8 ± 2.7

0.8554

Hearing stage (%) (N)

  

0.2398

 1

20% (1)

17% (5)

 2

40% (2)

31% (9)

 3

0% (0)

38% (11)

 4

40% (2)

14% (4)

AAO-HNS Functional Scale (%) (N)

  

0.0968

 1

67% (2)

30% (9)

 2

0% (0)

22% (6)

 3

0% (0)

22% (6)

 4

0% (0)

19% (5)

 5

0% (0)

7% (2)

 6

33% (1)

0% (0)

Tumarkin crisis (% yes) (N)

25% (2)

12% (4)

0.0562

Clinical MD group (%) (N)

  

0.6635

Metachronic/ Classic (type 1)

43% (3)

39% (13)

Synchronic/ Delayed (type 2)

0% (0)

0% (0)

Familiar History (type 3)

0% (0)

15% (5)

Migraine (type 4)

14% (1)

21% (7)

Autoimmunity (type 5)

43% (3)

24% (8)

  1. MDH Meniere Disease patients with high levels of cytokines, MDL Meniere Disease patients with low levels of cytokines, SD standard deviation.