Fig. 1: Differential expression of immune genes in PBMCs of children with ASD. | Genes & Immunity

Fig. 1: Differential expression of immune genes in PBMCs of children with ASD.

From: A multi-omics approach reveals dysregulated TNF-related signaling pathways in circulating NK and T cell subsets of young children with autism

Fig. 1

A Schematic diagram illustrating the experimental design. B Volcano plot showing 4 upregulated and 46 downregulated genes in ASD vs. control group. C–E Scatter plots demonstrating negative correlations between JAK3, CUL2, and CARD11 genes and the severity level of ASD symptoms. F–G Biclustering analysis of the 50 DEGs shows enrichment in several immune pathways based on the GO Biological Process and Hallmark MSigDB databases.

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