Fig. 5: Frequencies analysis of naïve and memory B and T cells. | Genes & Immunity

Fig. 5: Frequencies analysis of naïve and memory B and T cells.

From: Molecular analysis and immunological characterization of a founder mutation causing ARPC1B deficiency

Fig. 5

A Frequencies of naïve CD4+ T cells as a percentage of total CD4+ T cells in healthy controls, a heterozygous carrier and the patient. The error bars represent the SD. B CD4+ Terminal Effector Memory Re-expressing CD45RA (TEMRA), Effector Memory (EM), and Central Memory (CM) T cell frequencies as a percentage of total CD4+ T cells. The error bars represent the SD. C Frequencies of naïve CD8+ T cells as a percentage of total CD8+ T cells. D CD8+ Terminal Effector Memory Re-expressing CD45RA (TEMRA), Effector Memory (EM), and Central Memory (CM) T cell frequencies as a percentage of total CD8+ T cells. The error bars represent the SD. E Example of manual gating of CD27 vs IgD for healthy control (HC) and patient (P1) CD19+CD20+ B cells. Parental gating: CD45+ CD66b- CD19+ CD20+. S: switched, U: unswitched DN: double-negative. F Frequencies of B cell subsets as a percentage of total leukocytes in healthy controls, a heterozygous carrier, and the patient. The error bars represent the SD.

Back to article page