Fig. 9: Screening differentially metabolites among the three groups.

Heatmap showed top 50 differentially metabolites between (A) control and RT + anti-PD-1 groups, B control and RT + anti-PD-1 + si-Hspb1 groups, C between RT + anti-PD-1 and RT + anti-PD-1 + si-Hspb1 groups. KEGG analysis on differentially metabolites between (D) control and RT + anti-PD-1 groups, E control and RT + anti-PD-1 + si-Hspb1 groups, F between RT + anti-PD-1 and RT + anti-PD-1 + si-Hspb1 groups. G Venn diagram showing 11 common differential metabolites among three groups.