Fig. 2: Estimated survival distributions for patients with sialic acid storage disease (SASD). | Genetics in Medicine

Fig. 2: Estimated survival distributions for patients with sialic acid storage disease (SASD).

From: A cross-sectional quantitative analysis of the natural history of free sialic acid storage disease—an ultra-orphan multisystemic lysosomal storage disorder

Fig. 2

a Estimated overall survival distribution for patients with SASD (N = 106). Censored individuals are marked with a “+“. b Estimated survival distribution for SASD patients with an urinary excretion of free sialic acid above 6.37-fold (N = 29, black line) and below or equal to 6.37-fold of normal controls (N = 25, gray line). Censored individuals are marked with a “+“. Log-rank test, p < 0.001. c Estimated survival distribution for SASD patients with intracellular storage of free sialic acid above 7.37-fold (N = 37, black line) and below or equal to 7.37-fold of normal controls (N = 9, gray line). Intracellular free sialic acid storage was measured in fibroblasts. Censored individuals are marked with a “+“. Log-rank test, p = 0.014

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