Fig. 3: Location of NOTCH3 mutations between diagnosed CADASIL patients and individuals in the gnomAD database. | Genetics in Medicine

Fig. 3: Location of NOTCH3 mutations between diagnosed CADASIL patients and individuals in the gnomAD database.

From: The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1–6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7–34 pathogenic variant

Fig. 3

Pie charts displaying the differences in the number of mutations located in EGFr domains 1–6 versus 7–34, between European CADASIL patients and European individuals with a NOTCH3 mutation in gnomAD

Back to article page