Fig. 1 | Genetics in Medicine

Fig. 1

From: Clinical and genetic spectrum of children with congenital diarrhea and enteropathy in China

Fig. 1The alternative text for this image may have been generated using AI.

Histologic and immunohistochemical assessments of CODE patients. (a) Hematoxylin and eosin (H&E) analysis of the descending duodenum shows the loss of goblet cells and Paneth cells and the presence of apoptotic cells in patient 48. (b) H&E analysis of the small bowel shows hypoplasia of villi and crypt, with monocytic infiltration in all layers. (c) H&E analysis of colonic biopsy reveals histiocytic infiltration and irregular cellularity in patient 99. (d) Immunochemical staining shows CD1a marker positivity in the same patient.

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