Table 1 Grading of evidence

From: The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome

Grading of evidence

Category of evidence

Grading of evidence

Traditional

Guideline

Meta-analysis of randomized controlled trials

Ia

A

Randomized controlled trials

Ib

A

Well-designed and controlled study without randomization

IIa

B

Well-designed quasi-experimental study

IIb

B

Nonexperimental descriptive study

III

B

Expert opinion

IV

C