Fig. 3 | Genetics in Medicine

Fig. 3

From: Variants in MED12L, encoding a subunit of the mediator kinase module, are responsible for intellectual disability associated with transcriptional defect

Fig. 3

Recovery of RNA synthesis (RRS) following UV irradiation. Fibroblasts of individuals 1 (△) and 2 (○) show a moderately decreased level of RRS as compared with the normal control cell line (♦), similar to a MED12 mutated cell line (●). A MED13L mutated cell line (x) shows a more severely decreased RRS level, closer to the typical severely decreased level of RRS in a CSA defective cell line (■). Error bars represent standard errors of the mean.

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