Table 3 Hematological and biochemical values for iron deficiency (ID)/ID anemia (IDA)

From: Detection of iron deficiency in children with Down syndrome

 

No ID/IDA

IDa

IDAb

Hgb (g/dL)

 12–36 months

13.1 ± 1.1

12.1 ± .9

8.2 ± 3.4

n = 157 (88.2%)

n = 18 (10.1%)

n = 3 (1.7%)

 >36 months

14.2 ± 1.2

13.5 ± 1.2

10.3 ± 1.6

n = 643 (94.8%)

n = 28 (4.1%)

n = 7 (1.0%)

 All ages

14.0 ± 1.3

12.9 ± 1.3

9.7 ± 2.3

n = 800 (93.5%)

n = 46 (5.4%)

n = 10 (1.2%)

MCV (fL)

 12–36 months

87.4 ± 4.7

77.1 ± 9.8

66.4 ± 15.2

n = 142 (89.3%)

n = 15 (9.4%)

n = 2 (1.2%)

 >36 months

91.6 ± 5.7

86.3 ± 5.3

77.0 ± 6.5

n = 629 (96.2%)

n = 18 (2.8%)

n = 7 (1.1%)

 All ages

90.8 ± 5.8

82.1 ± 8.8

74.7 ± 9.1

n = 771 (94.8%)

n = 33 (4.1%)

n = 9 (1.1%)

RDW (%)

 12–36 months

14.6 ± 1.4

17.9 ± 2.6

20.6 ± 4.7

n = 142 (89.3%)

n = 15 (9.4%)

n = 2 (1.2%)

 >36 months

14.5 ± 9.7

16.5 ± 1.1

19.5 ± 1.8

n = 629 (96.2%)

n = 18 (2.8%)

n = 7 (1.1%)

 All ages

14.5 ± 8.8

17.2 ± 2.0

19.8 ± 2.3

n = 771 (94.8%)

n = 33 (4.1%)

n = 9 (1.1%)

Ferritin (ng/mL)

 12–36 months

51.8 ± 102.0

23.8 ± 24.9

12.3 ± 9.0

n = 134 (87.0%)

n = 17 (11.0%)

n = 3 (1.9%)

 >36 months

60.2 ± 49.8

19.2 ± 22.0

5.3 ± 1.9

n = 561 (94.4%)

n = 26 (4.4%)

n = 7 (1.2%)

 All ages

58.6 ± 63.3

21.0 ± 23.0

7.4 ± 5.7

n = 695 (92.9%)

n = 43 (5.7%)

n = 10 (1.3%)

CRP (mg/dL)

 12–36 months

0.6 ± 1.0

1.8 ± 4.6

2.6

n = 105 (88.2%)

n = 13 (10.9%)

n = 1 (0.8%)

 >36 months

0.7 ± 3.0

0.2 ± 0.4

0.6 ± 1.1

n = 524 (96.1%)

n = 17 (3.1%)

n = 4 (0.7%)

 All ages

0.7 ± 2.8

0.9 ± 3.1

 ± 1.3

n = 629 (94.7%)

n = 30 (4.5%)

n = 5 (0.7%)

Ferritin (ng/mL) in setting of normal CRP (<1.2 mg/dL)

 12–36 months

36.9 ± 25.0

22.2 ± 30.9

13.0

n = 94 (89.5%)

n = 10 (9.5%)

n = 1 (1.0%)

 >36 months

57.3 ± 45.8

8.6 ± 7.7

5.0 ± 0.0

n = 486 (96.2%)

n = 16 (3.2%)

n = 3 (0.6%)

 All ages

54.0 ± 43.7

13.8 ± 20.6

7.0 ± 4.0

n = 580 (95.1%)

n = 26 (4.3%)

n = 4 (0.7%)

TS (%)

 12–36 months

21.5 ± 9.2

9.5 ± 3.6

7.5 ± 6.4

n = 108 (84.4%

n = 17 (13.3%)

n = 3 (2.3%)

 >36 months

25.9 ± 11.5

10.5 ± 5.4

7.3 ± 3.9

n = 522 (94.6%)

n = 28 (5.1%)

n = 2 (0.4%)

 All ages

25.2 ± 11.3

10.1 ± 4.8

7.4 ± 4.5

n = 630 (92.2%)

n = 45 (6.6%)

n = 8 (1.2%)

  1. CRP   c-reactive protein, Hgb   hemoglobin, MCV  mean corpuscular volume, RDW   red cell distribution width, TS   transferrin saturation.
  2. aID = two abnormal biochemical markers of iron (low ferritin and low TS), or one abnormal biochemical marker plus elevated RDW.
  3. bIDA  =  ID plus a low hemoglobin concentration.