Table 2 Patient-Reported Outcomes Measurement Information System (PROMIS) domain scores

From: Evaluating the Patient-Reported Outcomes Measurement Information System scales in acute intermittent porphyria

Domains

N

Score

Patients with impairmenta N (%)

P valueb

Mean

SD

Range

Min

Max

Pain interference

229

55.1

11.3

40.7

77.0

92 (40.2)

<0.0001

Depression

231

50.9

10.3

38.2

78.1

50 (21.6)

0.18

Physical function

232

46.4

10.5

20.3

59.2

73 (31.5)

<0.0001

Fatigue

231

55.7

11.4

33.1

77.7

86 (37.2)

<0.0001

Anxiety

230

54.9

11.3

37.1

82.8

77 (33.5)

<0.0001

Sleep disturbance

231

53.6

10.6

30.5

77.5

65 (28.1)

<0.0001

Satisfaction with social roles

221

47.2

12.1

26.9

66.1

64 (29.0)

0.0007

  1. aImpairment defined as scores >1 SD or 10 units from the population mean.
  2. bP values from one-sample t test comparing observed sample mean with the general population mean of 50.
Back to article page