Fig. 3: Correlation of NEFL levels with clinical outcome measures, by assay method.
From: Neurofilament light chain levels correlate with clinical measures in CLN3 disease
Forest plot indicates the correlation coefficients along with 95% confidence limits. The horizontal axes describe the magnitude of the correlation coefficients, with <0 suggesting inverse relations and >0 suggesting positive relations. Adjusted p values are derived from the Stepdown Bonferroni method for multiple comparisons. Bold: p < 0.05. Bold italics: p < 0.01. ABC adaptive behavior composite, CGI clinical global impression, Cr creatine, CSF cerebrospinal fluid, Glx glutamatergic metabolites, NAA N-acetylaspartate, NEFL neurofilament light chain, PEA proximal extension assay, SimoaTM single molecule array, UBDRS Unified Batten Disease Rating Scale.
