Table 1 IQ scores per genotype.

From: Examination of the genetic factors underlying the cognitive variability associated with neurofibromatosis type 1

Genotype

Subjects (n = 495)

Mean FSIQ (SD)

Mean VIQ (SD)

Mean PIQ (SD)

Missense

72

89.3 (15.9)

92.9 (18.2)

89.1 (13.4)

Frameshift

134

88.8 (13.7)

91.6 (13.8)

88.1 (15.1)

Splicing

97

85.7 (16.0)

87.3 (16.4)

87 (16.2)

Nonsense

129

88.0 (14.2)

91.7 (14.4)

87.8 (14.2)

MI

38

85.7 (18.8)

86.8 (17.2)

87.4 (18.4)

CMD

25

72.8 (9.9)

77.4 (10.5)

73.2 (10.9)

  1. CMD chromosomal microdeletion, FSIQ full-scale intelligence quotient, MI miscellaneous intragenic, PIQ performance intelligence quotient, VIQ verbal intelligence quotient.
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