Fig. 2: CTNNA1 family 13. | Genetics in Medicine

Fig. 2: CTNNA1 family 13.

From: Loss-of-function variants in CTNNA1 detected on multigene panel testing in individuals with gastric or breast cancer

Fig. 2

a Pedigree of family 13. Red = gastric cancer, yellow = breast cancer and lobular carcinoma in situ (LCIS), gray = other cancers. (b, c) Hematoxylin & eosin (H&E) staining and α-E-catenin immunohistochemistry (IHC) of endoscopic biopsies of the family 13 proband’s diffuse signet-ring cell gastric adenocarcinoma (b) and the proband’s unaffected normal gastric mucosa (c). Images obtained at 20×.

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