Fig. 1: Expression of the major naturally occurring alternativeBRCA2 transcripts relative to full-length transcript. | Genetics in Medicine

Fig. 1: Expression of the major naturally occurring alternativeBRCA2 transcripts relative to full-length transcript.

From: Alternative mRNA splicing can attenuate the pathogenicity of presumed loss-of-function variants in BRCA2

Fig. 1: Expression of the major naturally occurring alternativeBRCA2 transcripts relative to full-length transcript.

Analysis by capillary electrophoresis of fluorescent RT-PCR products was performed to determine the relative expression level of isoforms in mouse embryonic stem cells (mESCs) transfected with wild type (WT) BRCA2 and in lymphoblastoid cell lines (LCLs) from healthy blood donors.

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