Fig. 2: Cumulative 10-year breast cancer risk distribution predicted by BOADICEA. | Genetics in Medicine

Fig. 2: Cumulative 10-year breast cancer risk distribution predicted by BOADICEA.

From: Validation of the BOADICEA model and a 313-variant polygenic risk score for breast cancer risk prediction in a Dutch prospective cohort

Fig. 2: Cumulative 10-year breast cancer risk distribution predicted by BOADICEA.The alternative text for this image may have been generated using AI.

Density plots of the cumulative 10-year risk calculated by BOADICEA for unaffected women and incident breast cancer cases. Including age and risk factors (left), including age and the PRS313 (middle), and the full model including age, risk factors and the PRS313. The dashed line shows the threshold of a 10-year risk of 2.5%. BOADICEA Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm, PRS polygenic risk score.

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