Table 1 Physical health conditions associated with fragile X syndrome (FXS).

Circulatory

 Heart valve replaced

3.64

14

0.13

11

4.01E-11

 First degree atrioventricular (AV) block

5.45

3.33

0.13

4.14

7.71E-11

 Heart valve disorders

9.09

25.4

1.85

12.5

6.29E-07

 Rheumatic disease of the heart valves

7.27

5.5

0.6

5.45

2.76E-06

Digestive

 Dyspepsia and other specified disorders of function of stomach

5.45

7.33

1.09

3.07

4.66E-10

 Other intestinal obstruction

3.64

24.5

0.38

13

2.37E-06

 Intestinal obstruction without mention of hernia

3.64

27.5

0.82

9.96

7.98E-06

 Irritable bowel syndrome

3.64

7.5

1

3.84

9.57E-06

Dental

 Gingival and periodontal diseases

10.91

4.83

3

2.65

5.34E-10

 Diseases of hard tissues of teeth

43.64

5

11.93

4.72

2.47E-08

 Disorders of tooth development

12.73

3.57

5.75

2.42

4.51E-06

 Diseases of pulp and periapical tissues

5.45

4

1.33

2.67

5.92E-06

 Disturbances in tooth eruption

12.73

3.14

5.42

2.31

6.59E-06

Endocrine/metabolic

 Short stature

3.64

21.5

0.64

5.89

1.51E-17

 Abnormal weight gain

7.27

5

1.38

3.04

1.16E-08

 Lack of normal physiological development

27.27

7.93

2.58

7.74

1.24E-08

 Hypokalemia

9.09

7.2

1.53

5.6

4.05E-06

 Electrolyte imbalance

12.73

9

2.64

6.99

4.74E-05

Genitourinary

 Retention of urine

3.64

22

1.11

5.7

2.94E-09

 Urinary incontinence

20

7.09

2.93

6.23

1.01E-07

 Other symptoms/disorders or the urinary system

30.91

9.71

14.13

5.47

1.80E-07

Other conditions

 Diseases of nail

20

5.45

3.69

4.22

8.51E-11

 Encounter for long-term (current) use of anticoagulants

5.45

76

1.02

32.46

6.71E-07

 Complication due to other implant and internal device

3.64

5.5

0.55

3.1

1.26E-06

 Cancer, suspected or other

3.64

30

0.35

8.79

3.60E-12

 Pleurisy; pleural effusion

3.64

21

1.02

7.45

2.74E-05