Table 2 Studies exploring Asian American attitudes, awareness, and experiences of genetic testing/genetic counseling (GT/GC).
From: Genetic counseling and testing for Asian Americans: a systematic review
First author, year | Research focus | Methodology | Total N (% Asian) | Asian group defined | Condition(s) studied | Other racial groups included in study |
|---|---|---|---|---|---|---|
Agather et al.56 | Genetic counseling experience | Qualitative semistructured interviews | 11 (0%) | Hmong | Not specified | White |
Catz et al.26 | Attitudes | Qualitative focus group | 55 (36%) | Chinese | Not specified | Black, Hispanic, White |
Chen et al.21 | Attitudes | Qualitative semistructured interviews | 49 (100%) | Chinese | Not specified | NA |
Chen et al.45 | Attitudes | Qualitative semistructured interviews | 42 (26%) | Nonspecific Asian | Autism spectrum disorder | Hispanic, Black, White |
Chen et al.20 | Awareness, attitudes | Qualitative semistructured interviews | 42 (26%) | Nonspecific Asian | Autism spectrum disorder | White, Hispanic, Black, Mixed |
Chen et al.5 | Attitudes | Qualitative semistructured interviews | 49 (100%) | Chinese | Autism spectrum disorder | NA |
Cheng et al.39 | Genetic counseling experience | Qualitative semistructured interviews and ethnographic observations | 25 (100%) | Chinese | Cancer | White |
Cheung et al.61 | Genetic testing uptake, family communication of test results | Quantitative cross-sectional survey | 1103 (6%) | Nonspecific Asian | BRCA1/2 | White, Ashkenazi Jewish, Hispanic, Black |
Culhane-Pera et al.40 | Attitudes | Qualitative semistructured interviews and focus groups | 47 (100%) | Hmong | Not specified | NA |
Dixson et al.59 | Genetic counseling experience | Review of educational program | 0 (0%) | Hmong, Cambodian, Laotian, and Vietnamese | Thalassemia, G6PD deficiency, cleft lip and palate, congenital heart defects, chromosome abnormalities | NA |
Fehniger et al.32 | Genetic testing uptake, family communication of test results | Qualitative semistructured interviews | 73 (19%) | Nonspecific Asian | BRCA1/2 | Black, Hispanic, White, Mixed |
Fehniger et al.54 | Attitudes | Randomized controlled trial | 1261 (19%) | Nonspecific Asian | Breast cancer | White, Hispanic, Black |
Floyd et al.46 | Attitudes | Qualitative semistructured interviews | 24 (29%) | Nonspecific Asian | Prenatal not specified | Hispanic, White |
George52 | Genetic counseling experience | Quantitative cross-sectional survey | 41 (0%) | Nonspecific Asian | Prenatal not specified | NA |
Glanz et al.41 | Attitudes, genetic testing uptake | Quantitative cross-sectional survey | 426 (79%) | Japanese | Colorectal cancer | Hawaiian, White |
Glenn et al.22 | Attitudes | Qualitative semistructured interviews | 33 (52%) | Nonspecific Asian, South Asian, Chinese, Korean, Filipino | Breast and ovarian cancer | White, Hispanic, Black |
Grimes et al.65 | Attitudes | Quantitative cross-sectional survey | 633 (9%) | Chinese | Autism spectrum disorder | White, Hispanic |
Hall et al.37 | Attitudes | Quantitative cross-sectional survey | 86859 (14%) | Nonspecific Asian | Not specified | White, Black, Hispanic, Native American/Alaskan, Pacific Islander, multiple races |
Harrison et al.57 | Genetic testing experience | Quantitative cross-sectional survey | 1281 (10%) | Nonspecific Asian | Hemochromatosis and iron overload | White, Black, Hispanic |
Heidi et al.33 | Genetic testing uptake | Quantitative review of medical records | 195 (3%) | Nonspecific Asian | BRCA1/2 | Hispanic, White, Black |
Joseph et al.58 | Genetic counseling experience | Qualitative semistructured interviews and ethnographic observations | 124 (20%) | Chinese | Cancer | White, Hispanic |
Jun et al.23 | Genetic testing uptake | Qualitative semistructured interviews | 10 (100%) | Korean | Prenatal not specified | NA |
Krakow et al.28 | Awareness, genetic testing uptake | Quantitative cross-sectional survey | 3285 (4%) | Nonspecific Asian | Not specified | White, Black, Hispanic |
Krieger et al.64 | Genetic counseling experience | Qualitative semistructured interviews | 6 (100%) | Hmong | Not specified | NA |
Kupperman et al.53 | Attitudes, genetic testing uptake | Quantitative cross-sectional survey | 827 (27%) | Nonspecific Asian | Down syndrome | White, Hispanic, Black |
Landry et al.43 | Attitudes | Quantitative cross-sectional survey | 1487 (4%) | Nonspecific Asian | Not specified | White, Hispanic, Black |
Leader et al.27 | Genetic testing awareness | Qualitative focus group | 32 (100%) | Indian, Pakistani | Cancer | NA |
Learman et al.60 | Attitudes | Quantitative cross-sectional survey | 999 (26%) | Nonspecific Asian | Down syndrome | Black, Hispanic, White |
Levy et al.30 | Genetic testing uptake | Quantitative review of medical records | 1474 (5%) | Nonspecific Asian | BRCA1/2 | White, Black, Hispanic, Jewish |
Manrriquez et al.19 | Referral rates, genetic testing uptake | Quantitative review of medical records | 236 (13%) | Nonspecific Asian | Ovarian cancer | White, Hispanic, Black |
McGrath et al.25 | Genetic testing awareness | Qualitative semistructured interviews | 19 (53%) | Japanese | Not specified | Samoan Americans |
Mittman et al.36 | Genetic counseling experience | Quantitative cross-sectional survey | 59 (0%) | Nonspecific Asian | Prenatal not specified | White, Black, Latin American |
Olaya et al.34 | Genetic testing uptake | Quantitative retrospective cohort review | 213 (5%) | Nonspecific Asian | BRCA1/2 | White, Hispanic, Black |
Pagán et al.24 | Genetic testing awareness | Quantitative cross-sectional survey | 25364 (0%) | Nonspecific Asian | Cancer | White, Hispanic, Black |
Palmer et al.35 | Genetic testing uptake | Quantitative cross-sectional survey | 30 (17%) | Nonspecific Asian | GJB2/GJB6 | White, Hispanic, Black, Hawaiian/other Pacific Islander |
Palmer et al.38 | Attitudes | Quantitative cross-sectional survey | 139 (17%) | Nonspecific Asian | Deafness | White, Hispanic |
Pasick et al.29 | Genetic counseling uptake | Quantitative cross-sectional survey | 709 (16%) | Nonspecific Asian | Breast and ovarian cancer | Hispanic, White, Black, multiracial |
Ramirez et al.42 | Attitudes | Quantitative cross-sectional survey | 49 (20%) | Nonspecific Asian | Breast cancer | Black, Hispanic, Native American, Appalachian |
Ricker et al.62 | Family communication of test results | Quantitative cross-sectional survey | 136 (19%) | Nonspecific Asian | Cancer | White, Hispanic, Black |
Saucier et al.50 | Genetic testing uptake | Quantitative cross-sectional survey | 157 (18%) | Nonspecific Asian | Prenatal not specified | White, Black, Hispanic |
Sayres et al.55 | Attitudes | Quantitative cross-sectional survey | 3164 (6%) | Nonspecific Asian | Prenatal not specified | American Indian or Alaska Native, Black or African-American, Native Hawaiian or Pacific Islander, White, Hispanic |
Sim et al.47 | Attitudes | Quantitative cross-sectional survey | 86 (100%) | Chinese | Thalassemia | NA |
Simons-Morton et al.31 | Genetic testing uptake | Quantitative review of medical records | 8499 (0%) | Nonspecific Asian | Type 2 diabetes mellitus | Black, American-Indian, Hispanic, White |
Tischler et al.48 | Attitudes | Quantitative cross-sectional survey | 114 (31%) | Nonspecific Asian | Prenatal not specified | White, Black, Hispanic, Middle Eastern, Multiracial |
Tsai et al.44 | Attitudes | Qualitative semistructured interviews | 23 (100%) | Chinese, Vietnamese, Korean, Malaysian, Japanese, Singaporean, Indonesian, Filipino | Not specified | NA |
Tucker et al.63 | Attitudes, family communication of test results | Quantitative cross-sectional survey | 75964 (15%) | Nonspecific Asian | Hemochromatosis | White, Hispanic, Black, American Indian, Pacific Islander |
Winkelman et al.49 | Attitudes | Quantitative cross-sectional survey | 1006 (3%) | Nonspecific Asian | Prenatal not specified | White, Black or African-American, multiracial |
